Should supplemental estrogen be used as steroid-sparing agents in women with asthma?

weeks, pneumatosis and pneumoperitoneum had completely resolved. We suggest that a smouldering gastrointestinal CMV disease proven by biopsy 8 weeks before and incompletely suppressed by oral acyclovir was the cause of pneumatosis in our patient. Leukocyte CMV immediate early antigen remained negative, but this is known in an isolated gastrointestinal CMV disease, even if no specific suppressive therapy is used.3 Our observation is strikingly similar to the case reported by Mannes et all and emphasizes the fact mentioned by Rubin4 that gastrointestinal CMV infection may present in this peculiar form and may respond to antiviral treatment. An additional symptomatic therapeutic effect of metronidazole, however, cannot be excluded.